Application Of Transgenic Animals Wikipedia

Using transgenic mice as test systems eg protein CFTR secretion.

Application of transgenic animals wikipedia. Transgenic animals are those that have been genetically modified. Clotting factors vaccines monocl onal antibodies growth factors collagen fibrinogen. Transgenic animals are animals that are gene tically altered to have traits t hat mimic symptoms of spe cific.

One favoured method involves the inoculation of the DNA into the pronucleus of a fertilised ovum followed by implantation into pseudo pregnant females. Transgenic constructs bearing the immunoglobulin A LA gene have successfully introduced into pigs sheep and mice in an attempt to increase resistance against infections. The animal which are genetically engineered called as transgenic animals produce and secrete such novel therapeutic proteins throughout their life.

These animals can be helpful in producing organs growth hormones and useful proteins for the humans. There have been numerous reports and applications of transgenic plants in agriculture mainly to benefit the producer. 1 Resistance to Biotic Stresses 2 Resistance to Abiotic Stresses 3 Improvement of Crop Yield and Quality 4 Transgenic Plants with Improved Nutrition5 Commercial Transgenic Crop Plants and 6 Transgenic Plants as Bioreactors.

Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Transgenic applications used in animals to enhance disease resistance include the transfer of major histocompatibility complex genes T-cell receptor genes and immunoglobulin genes. Many of these crosses of transgenic animals have these similar effects in the production of such products.

Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny. They provide genetic models of va rious human d. Applications of animal transgenesis may be divided into three major categories.

2 Introduce genes for faster growth rates or leaner growth patterns. The application of transgenic animals showed that within the next five to eight years genetically modified animals will play a significant and important role in the biomedical field in particular via the production of valuable pharmaceutical proteins and the supply of xenografts. Contents Transgenic animals are more widely used for various purposes.